Endocrine Abstracts

Purpose: Diabetes is one of the most common metabolic disease which has got many peptide hormones have in its etiology. Phoenixin (PNX), a recently discovered neuropeptide appears to have a role in energy management and metabolism through regulating insulin neogenesis and secretion, according to research. There is no research has been studied on the association between diabetes and PNX levels. The aim of the study was to see if there was a relation between PNX levels in the se...

Introduction: Acromegaly is a clinical syndrome associated with excess growth hormone. The present study aimed to investigate sarcopenia and frailty, which could affect mortality and morbidity, in patients with acromegaly.Method: Twenty outpatients diagnosed with acromegaly were included in the study. The hand muscle strength of the patients was measured by electronic hand dynamometer (Model EH101, Zhongshan Camry Electronic Co. Ltd. China). Computed tom...

Aim and objective: The aims of this study were to determine the incidence of breast cancer molecular subgroups, to investigate the relationship between autoimmune thyroid disease and prognostic and predictive factors in patients who were diagnosed with breast cancer.Materials and methods: One hundred one patients who were followed up with the diagnosis of breast cancer at our Endocrinology and Medical Oncology Departments were included. Patients are divi...

Introduction: Correction of Insulin resistance (IR) and dyslipidemic conditions of obese patients is important for the prevention of cardiovascular disease (CVD). The aim of our study is to determine the relationship between IR and non-high-density lipoprotein cholesterol (non-HDL-C) in obese patients.Material and methods: 248 patients over the age of eighteen, non-pregnant, followed with a diagnosis of obesity but did not receive the treatment of metfor...

Introduction: Diabetes insipidus (di) is a water metabolism disorder caused by antidiuretic hormone pathologies. In this study, we evaluated, retrospectively, pituitary hormone profiles and pituitary magnetic resonance imaging (mri) findings of patients with di.Material and methods: After local ethic committee approval, 300 patients were evaluated retrospectively. Patients with a history of pituitary surgery and/or radiotherapy were excluded. Luteinizing...

Introduction: Scleredema is a rare skin disease, clinically presents as diffuse, painless induration, and thickening of skin. It primarily affects the upper part of body and usually occurs in association with diabetes mellitus, infections or monoclonal gammopathy. We discussed a case of scleredema in patient with history of diabetes mellitus.Case report: A 54-year-old woman with history of long-standing, poorly-controlled diabetes mellitus, hypertension,...

Introduction: Pituitary apoplexy results from haemorrhagic infarction of a pre-existing pituitary adenoma or within physiologically enlarged gland. Pituitary apoplexy during pregnancy is rare but serious event with significant morbidity and mortality if not recognised in time. Pituitary apoplexy is characterised by sudden onset of headache, nausea, vomiting, visual disturbances, eye movements restricted and varying degrees of pituitary insufficiency and accompanied by change o...

Objective: The frequency of differentiated thyroid cancer in the Graves’ disease are controversial. The aim of this study was to evaluate the frequency of thyroid cancers in patients operated because of Graves’ disease.Subjects and methods: Sixty-six patients in whom thyroidectomy was performed because of Graves’ disease between 2001 and 2012 were evaluated retrospectively. Patients who had received radioactive iodine treatment and externa...

Aim: Mean platelet volume (MPV) is considered a new indicator of atherosclerosis. Activated platelets and subclinical inflammation predispose to create for atherosclerotic heart disease. Larger platelets are metabolically more active than smaller ones and have more protrombotic potential. We have recently demonstrated that MPV levels in Hashimoto’s patients tend to be higher than healthy controls even if in euthyroid state. In present study we aimed to investigate a relat...

Primary hyperparathyroidism is a condition related with cardiovascular mortality and morbidity. Aim of this study is to investigate whether there is a difference between healthy controls, hypercalcemic patients with surgical decision and normocalcemic primary hyperparathyroidism patients for parameters like metabolic cardiovascular risk factors, carotis intima media thickness and pulse wave velocity and if there is a difference at patients with surgical decision 6 months after...